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Researchers employ the peptide in in vitro and ex vivo models to probe the signaling cascades that regulate dendritic spine density, synaptic connectivity, and long-term potentiation

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History Scientific interest in NNMT increased substantially during the early 2000s as researchers discovered its involvement in metabolic regulation, cellular methylation processes, and adipose tissue function

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Any references to senescence, cellular aging, or regeneration are included strictly for literature indexing and experimental context

Immune disorders such as Graves disease and lupus